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The candidate will be required to spearhead research into mechanism of idiopathic scoliosis and spinal cord regeneration using zebrafish and mouse models. This will involve the analysis of ciliary activity and Urotensin signalling mechanisms to understand how dysfunction of these biological processes underlie the development of spine abnormalities in vertebrates and idiopathic scoliosis in humans. The candidate will be required to perform experiments entailing immunofluorescence microscopy, in situ hybridization, protein chemistry, dissection of zebrafish and mouse organs and tissues, RT-qPCR, and chromatin immunoprecipitation, assembly of manuscripts for publication and exploration of additional funding through schemes like NMRC-YIRG to take the research to new directions.Requirement:
Experience with zebrafish genetics, immunofluorescence microscopy, in situ hybridization, chromatin immunoprecipitation will be necessary. Experience with mouse genetics will be an added advantage. Must be highly motivated, proficient in language and able to function independently.
The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.
Type of Employment : Full-Time
Work Location : Biopolis
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